Understanding Late-Onset Pompe Disease
HealthLate-onset Pompe disease (LOPD), also known as acid alpha-glucosidase deficiency, is a rare genetic disorder that primarily affects adults. It's caused by a deficiency in the enzyme acid alpha-glucosidase (GAA), leading to a buildup of glycogen in muscles, particularly...
Late-onset Pompe disease (LOPD), also known as acid alpha-glucosidase deficiency, is a rare genetic disorder that primarily affects adults. It's caused by a deficiency in the enzyme acid alpha-glucosidase (GAA), leading to a buildup of glycogen in muscles, particularly in the limbs, respiratory system and heart. While initially identified as a childhood disease, the adult-onset form is now more commonly diagnosed. Keep reading to...